Net reclassification improvement and integrated discrimination improvement: new standards for evaluating the incremental value of stress imaging for risk assessment.
نویسندگان
چکیده
منابع مشابه
Comparison of Bayesian and Frequentist Methods in Estimating the Net Reclassification and Integrated Discrimination Improvement Indices for Evaluation of Prediction Models: Tehran Lipid and Glucose Study
Introduction: The Frequency-based method is commonly used to estimate the Net Reclassification Improvement (NRI)- and Integrated Discrimination Improvement (IDI) indices. These indices measure the magnitude of the performance of statistical models when a new biomarker is added. This method has poor performance in some cases, especially in small samples. In this study, the performance of two Bay...
متن کاملUsefulness of exercise test and myocardial perfusion-gated single photon emission computed tomography to improve the prediction of major events.
BACKGROUND The incremental prognostic value of myocardial perfusion-gated single photon emission computed tomography (MPGS) compared with exercise test has not yet been properly evaluated. METHODS AND RESULTS Five thousand six hundred seventy-two consecutive patients with known or suspected coronary disease undergoing exercise MPGS between 1997 and 2007 were included. Three-year predictive mo...
متن کاملImprovement of risk prediction by genomic profiling: reclassification measures versus the area under the receiver operating characteristic curve.
Reclassification is observed even when there is no or minimal improvement in the area under the receiver operating characteristic curve (AUC), and it is unclear whether it indicates improved clinical utility. The authors investigated total reclassification, net reclassification improvement, and integrated discrimination improvement for different DeltaAUC using empirical and simulated data. Empi...
متن کاملClinically relevant measures of fit? A note of caution.
Risk reclassification methods have become popular in the medical literature as a means of comparing risk prediction models. In this issue of the Journal, Pencina et al. (Am J Epidemiol. 2012;176(6):492-494) present further results for continuous measures of model discrimination and describe their characteristics in nested models with normally distributed variables. Measures include the change i...
متن کاملCardiorespiratory fitness and classification of risk of cardiovascular disease mortality.
BACKGROUND Cardiorespiratory fitness (fitness) is associated with cardiovascular disease (CVD) mortality. However, the extent to which fitness improves risk classification when added to traditional risk factors is unclear. METHODS AND RESULTS Fitness was measured by the Balke protocol in 66 371 subjects without prior CVD enrolled in the Cooper Center Longitudinal Study between 1970 and 2006; ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Circulation. Cardiovascular imaging
دوره 6 4 شماره
صفحات -
تاریخ انتشار 2013